Generic approach for the development of genetic sexing strains for SIT applications
Closed for Proposals
Project Type
Coordinated Research ProjectProject Code
D44003
CRP
2192
Approved Date
04.12.2018Project Status
Active - OngoingStart Date
27.03.2019Expected End Date
28.03.2025Completed Date
04.08.2025Participating Countries
Argentina, Australia, Canada, Switzerland, Cameroon, China, Czech Republic, Germany, France, United Kingdom of Great Britain and Northern Ireland, Greece, Guatemala, Israel, Italy, Mexico, Pakistan, Thailand, United States of America, South AfricaDescription
The objective of this CRP is to develop generic approaches for the development of genetic sexing strains for sterile insect technique applications will have the following outputs:
-Assessment of at least two generic strategies that can be followed to solving the problem of developing GSS: 1) the development of strains that have conditional, sex-specific (female-specific) lethal phenotypes and 2) strains with altered sex determination and development pathways resulting in skewed sex ratios (male-only).
-Assessment of approaches to successfully implement these strategies and of particular interest are those that are the most widely applicable with respect to the number of target species to which the solution could be implemented with a minimum of research and development.
-Use of generic approaches to develop genetic sexing strains that reduce research and development time and costs, allowing SIT programs to be more readily developed and implemented against more pest species.
Objectives
The main objective of this CRP is the development and evaluation of generic approaches for the construction of genetic sexing strains (GSS) to be used for sterile insect technique (SIT) applications, as part of AW-IPM programs, to control populations of agricultural pests and disease vectors.
Specific Objectives
To develop generic strategies for the construction of GSS for SIT applications
To assess the efficiency, applicability and the range of the species transferability of the generic approaches
To evaluate, at small scale, GSS developed through the generic approaches