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          Generic approach for the development of genetic sexing strains for SIT applications

          Open for proposals

          Project Type

          Coordinated Research Project

          Project Code

          D44003

          CRP

          2192

          Approved Date

          4 December 2018

          Status

          Active - Ongoing

          Start Date

          27 March 2019

          Expected End Date

          28 March 2025

          Participating Countries

          Argentina
          Australia
          Cameroon
          Canada
          China
          Czech Republic
          France
          Germany
          Greece
          Guatemala
          Israel
          Italy
          Mexico
          Pakistan
          South Africa
          Switzerland
          Thailand
          United Kingdom of Great Britain and Northern Ireland
          United States of America

          Description

          The objective of this CRP is to develop generic approaches for the development of genetic sexing strains for sterile insect technique applications will have the following outputs:

          -Assessment of at least two generic strategies that can be followed to solving the problem of developing GSS: 1) the development of strains that have conditional, sex-specific (female-specific) lethal phenotypes and 2) strains with altered sex determination and development pathways resulting in skewed sex ratios (male-only).

          -Assessment of approaches to successfully implement these strategies and of particular interest are those that are the most widely applicable with respect to the number of target species to which the solution could be implemented with a minimum of research and development.

          -Use of generic approaches to develop genetic sexing strains that reduce research and development time and costs, allowing SIT programs to be more readily developed and implemented against more pest species.

          Objectives

          The main objective of this CRP is the development and evaluation of generic approaches for the construction of genetic sexing strains (GSS) to be used for sterile insect technique (SIT) applications, as part of AW-IPM programs, to control populations of agricultural pests and disease vectors.

          Specific objectives

          To develop generic strategies for the construction of GSS for SIT applications

          To assess the efficiency, applicability and the range of the species transferability of the generic approaches

          To evaluate, at small scale, GSS developed through the generic approaches

          To develop generic strategies for the construction of GSS for SIT applications

          To assess the efficiency, applicability and the range of the species transferability of the generic approaches

          To evaluate, at small scale, GSS developed through the generic approaches

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