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          Body Fat and its Relationship with Metabolic Syndrome Indicators in Overweight Pre-Adolescents and Adolescents

          Closed for proposals

          Project Type

          Coordinated Research Project

          Project Code

          E43019

          CRP

          853

          Approved Date

          2 September 2005

          Status

          Closed

          Start Date

          15 December 2005

          Expected End Date

          3 June 2011

          Completed Date

          3 June 2011

          Objectives

          To establish the relationship between body mass index (BMI) and body fat and explore their association with indicators of metabolic syndrome in pre-adolescents and adolescents from different ethnic groups.

          Specific objectives

          1. To define the relationship between body mass index (BMI) and body fat in pre-adolescents of 9 years at the first stage of puberty (Tanner Stage 1: T1) and adolescents of 16 years old at the 4th and 5th stages of puberty (T4-5) from different ethnic groups.

          2. To determine the relationship between body fat and insulin, glucose and blood pressure in overweight pre-adolescents and adolescents from different ethnic groups.

          Impact

          Data from this CRP will assist the health policy makers in Member States in their efforts to prevent and control obesity related non-communicable diseases. At the start of the CRP, data was lacking in many Member States, so this data will be a baseline for comparison with future data following interventions. The skills developed in China, Malaysia and Morocco are being utilised in the follow-on CRP E4.30.24, "Nuclear techniques to assess body composition in children and adolescents as a risk factor in the development of chronic diseases". Morocco is a key partner in TC Regional project RAF6042 "Applying Nuclear Techniques to Design and Evaluate Interventions to Reduce Obesity and Related Health Risks", which started in 2012 and involves 12 African Member States. The CSI from Malaysia will be the lead coordinator for a new RAS Regional project for the 2014-2015 cycle "Preventing overweight and obesity, and promoting physical activity among children and adolescents in Asia", which will involve 19 countries in the region; emphasising the importance of the topic, and of synergies between the Technical Cooperation programme and CRP's in nutrition.

          Relevance

          The CRP is highly relevant, as WHO Member States will adopt the Global Monitoring Framework on Noncommunicable Diseases during the World Health Assembly in May 2013. The framework comprises nine global targets and 25 indicators, including one related to adolescent obesity.

          CRP Publications

          Type

          Research Report

          Year

          2010

          Publication URL

          http://www.nature.com/ejcn/journal/v64/n10/full/ejcn2010128a.html

          Description

          CAMPBELL, C.P., et al., Predictors of physical activity energy expenditure in Afro-Caribbean children, Eur. J. Clin. Nutr. 64 (2010) 1093-1100.

          Country/Organization

          Jamaica

          Type

          Research Report

          Year

          2012

          Publication URL

          http://www.indianpediatrics.net/feb2012/109.pdf

          Description

          JOSE, B. et al., Serum magnesium in overweight children, Indian Pediatr. 49 (2012) 109-112.

          Country/Organization

          India

          Type

          Research Report

          Year

          2012

          Description

          BARZIN, M., et al., The association of anthropometric indices in adolescence with the occurrence of the metabolic syndrome in early adulthood: Tehran Lipid and Glucose Study (TLGS).

          Country/Organization

          Iran

          Type

          Research Report

          Year

          2011

          Description

          WANG, X. et al., A bioelectrical impedance prediction equation for the assessment of total body water and fat-free mass among Chinese children aged 7-10 year. Chinese Journal of Prevention and Control of Chronic Disease 19 (2011) 441-444.

          Country/Organization

          China

          Type

          Research Report

          Year

          2010

          Description

          MIRMIRAN, P., et al., Performance of different definitions of metabolic syndrome for children and adolescents in a 6-year follow-up: Tehran Lipid and Glucose Study (TLGS). Diabetes Res. Clin. Pract. 89 (2010) 327-333.

          Country/Organization

          Iran

          Type

          Research Report

          Year

          2010

          Publication URL

          http://www.ncbi.nlm.nih.gov/pubmed/22691926

          Description

          QUAH, Y.V., POH, B.K., ISMAIL, M.N., Metabolic syndrome based on IDF criteria in a sample of normal weight and obese school children, Malays. J. Nutr. 16 (2010) 207-217.

          Country/Organization

          Malaysia

          Type

          Research Report

          Year

          2009

          Description

          SANTOS, C.D.L. et al., Influencia do deficit de estatura nos desvios nutricionais em adolescentes e pré-adolescentes. Revista de Nutri??o 22 (2009) 187-194.

          Country/Organization

          Brazil

          Type

          Research Report

          Year

          2010

          Publication URL

          http://www.karger.com/Article/Pdf/321532

          Description

          NASREDDINE, L., et al., 2010, Metabolic Syndrome and Insulin Resistance in Obese Pre-Pubertal Children in Lebanon: A Primary Health Concern. Ann. Nutr. Metabol. 57 (2010) 135-142.

          Country/Organization

          Lebanon

          Type

          Research Report

          Year

          2011

          Publication URL

          http://journals.cambridge.org/download.php?file=/BJN/BJN106_09/S0007114511001681…

          Description

          LIU, A., et al., Ethnic differences in the relationship between body mass index and percentage body fat among Asian children from different backgrounds, Bri. J. Nutr. 106 (2011) 1390-1397.

          Country/Organization

          China

          Type

          Research Report

          Year

          2011

          Publication URL

          http://www.biomedcentral.com/content/pdf/1471-2458-11-500.pdf

          Description

          LIU, A., et al., Ethnic differences in body fat distribution among Asian pre-pubertal children: a cross-sectional multicenter study, BMC Public Health 11 (2011) 500-506.

          Country/Organization

          China

          Type

          Research Report

          Year

          2012

          Publication URL

          http://www.scielo.br/pdf/abc/v98n1/en_aop10911.pdf

          Description

          CLEMENTE, A.P. et al., Mild stunting is associated with higher blood pressure on overweight adolescents, Arq. Bras. Cardiol. 98 (2012) 6-12.

          Country/Organization

          Brazil

          Type

          Research Report

          Year

          2011

          Publication URL

          http://www.biomedcentral.com/content/pdf/1471-2458-11-333.pdf

          Description

          WEE, B.S. et al., Risk of metabolic syndrome among children living in metropolitan Kuala Lumpur: a case control study, BMC Public Health 11 (2011) 333-339

          Country/Organization

          Malaysia

          Type

          Research Report

          Year

          2009

          Description

          LIU, A., et al., Relationship between anthropometric parameters and lipids profiles (2009) (published in Chinese)

          Country/Organization

          China

          Type

          Review

          Year

          2011

          Description

          MARTINS, V.J.B. et al., Long-lasting effects of undernutrition, Int. J. Environ. Res. Public Health, 8 (2011) 1817-1846.

          Country/Organization

          Brazil

          Type

          Research Report

          Year

          2012

          Publication URL

          http://www.nature.com/ejcn/journal/v66/n10/full/ejcn201289a.html

          Description

          RAMIREZ, E., et al., Body composition prediction equations based on deuterium oxide dilution method in Mexican children: a national study, Eur. J. Clin. Nutr. 66 (2012) 1099-1103.

          Country/Organization

          Mexico

          Type

          Research Report

          Year

          2011

          Publication URL

          http://www.nature.com/ejcn/journal/v65/n12/full/ejcn2011122a.html

          Description

          LIU, A., et al., Validation of bioelectrical impedance analysis for total body water assessment against the deuterium dilution technique in Asian children, Eur. J. Clin. Nutr. 65 (2011) 1321-1327.

          Country/Organization

          China

          Type

          Research Report

          Year

          2011

          Description

          CLEMENTE, A.P. et al., índice de massa corporal de adolescentes: compara??o entre diferentes referências, Revista Paulista de Pediatria 29 (2011) 171-177.

          Country/Organization

          Brazil

          Type

          Research Report

          Year

          2012

          Description

          HAMRANI, A., et al., Fat-free mass prediction model for Moroccan adolescents by bioelectrical impedance analysis using deuterium oxide dilution as a reference, Int. J. Body. Comp. Res. 10 (2012) 107-114.

          Country/Organization

          Morocco

          Type

          Research Report

          Year

          2011

          Publication URL

          http://informahealthcare.com/doi/abs/10.3109/17477166.2011.583658

          Description

          POH, B.K., et al., Waist circumference percentile curves for Malaysian children and adolescents aged 6.0-16.9 years, Int. J. Pediatr. Obes. 6 (2011) 229-235.

          Country/Organization

          Malaysia

          Type

          Research Report

          Year

          2012

          Publication URL

          http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489944/pdf/jhpn0030-0281.pdf

          Description

          KHAN, A.I., et al., Body composition of Bangladeshi children: comparison and development of leg-to-leg bioelectrical impedance equations, J. Health Popul. Nutr. 30 (2012) 281-290.

          Country/Organization

          Bangladesh

          Type

          Research Report

          Year

          2010

          Description

          LIU, A., et al., Waist circumference cut-off values for the prediction of cardiovascular risk factors clustering in Chinese school-aged children: a cross-sectional study. BMC Public Health 10 (2010) 82-90.

          Country/Organization

          China

          Type

          Research Report

          Year

          2010

          Publication URL

          http://www.hindawi.com/journals/jnume/2010/943070/

          Description

          SANTOS, C.D.L. et al., Adolescents with mild stunting show alterations in glucose and insulin metabolism. J. Nutr. Metabol. (2010), Article ID 943070, 6 pages.

          Country/Organization

          Brazil

          Type

          Research Report

          Year

          2011

          Publication URL

          http://www.jped.com.br/ArtigoDetalhe.aspx?varArtigo=2180&idioma=pt-BR

          Description

          CLEMENTE, A.P. et al., Mild stunting is associated with higher body fat: study of a low-income population, J. Paediatr. (Rio J.) 87 (2011) 138-144.

          Country/Organization

          Brazil

          Type

          Research Report

          Year

          2011

          Description

          HOSSEINI-ESFAHANI, F., et al., Trends in risk factors for cardiovascular disease among Iranian adolescents: the Tehran Lipid and Glucose Study, 1999-2008. J. Epidemiol. 21 (2011) 319-328.

          Country/Organization

          Iran

          Type

          Research Report

          Year

          2012

          Publication URL

          http://informahealthcare.com/doi/pdf/10.3109/03014460.2012.655776

          Description

          NASREDDINE, L., et al., Obesity is associated with insulin resistance and components of the metabolic syndrome in Lebanese adolescents, Ann. Hum. Biol. 39 (2012) 122-128.

          Country/Organization

          Lebanon

          Type

          Research Report

          Year

          2012

          Publication URL

          http://www.hindawi.com/journals/jnume/2012/510458/

          Description

          MEHDAD, S., et al., Body mass index, waist circumference, body fat, fasting blood glucose in a sample of Moroccan adolescents aged 11-17 years, J. Nutr. Metabol. (2012) Article ID 510458, 7 pages.

          Country/Organization

          Morocco

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