Body Fat and its Relationship with Metabolic Syndrome Indicators in Overweight Pre-Adolescents and Adolescents
Closed for Proposals
Project Type
Coordinated Research ProjectProject Code
E43019
CRP
853
Approved Date
02/09/2005Project Status
ClosedStart Date
15/12/2005Expected End Date
03/06/2011Completed Date
03/06/2011Objectives
To establish the relationship between body mass index (BMI) and body fat and explore their association with indicators of metabolic syndrome in pre-adolescents and adolescents from different ethnic groups.
Specific Objectives
1. To define the relationship between body mass index (BMI) and body fat in pre-adolescents of 9 years at the first stage of puberty (Tanner Stage 1: T1) and adolescents of 16 years old at the 4th and 5th stages of puberty (T4-5) from different ethnic groups.
2. To determine the relationship between body fat and insulin, glucose and blood pressure in overweight pre-adolescents and adolescents from different ethnic groups.
Impact
Data from this CRP will assist the health policy makers in Member States in their efforts to prevent and control obesity related non-communicable diseases. At the start of the CRP, data was lacking in many Member States, so this data will be a baseline for comparison with future data following interventions. The skills developed in China, Malaysia and Morocco are being utilised in the follow-on CRP E4.30.24, "Nuclear techniques to assess body composition in children and adolescents as a risk factor in the development of chronic diseases". Morocco is a key partner in TC Regional project RAF6042 "Applying Nuclear Techniques to Design and Evaluate Interventions to Reduce Obesity and Related Health Risks", which started in 2012 and involves 12 African Member States. The CSI from Malaysia will be the lead coordinator for a new RAS Regional project for the 2014-2015 cycle "Preventing overweight and obesity, and promoting physical activity among children and adolescents in Asia", which will involve 19 countries in the region; emphasising the importance of the topic, and of synergies between the Technical Cooperation programme and CRP's in nutrition.
Relevance
The CRP is highly relevant, as WHO Member States will adopt the Global Monitoring Framework on Noncommunicable Diseases during the World Health Assembly in May 2013. The framework comprises nine global targets and 25 indicators, including one related to adolescent obesity.
CRP Publications
Brazil
Research Report
2011
CLEMENTE, A.P. et al., índice de massa corporal de adolescentes: compara??o entre diferentes referências, Revista Paulista de Pediatria 29 (2011) 171-177.
Brazil
Review
2011
MARTINS, V.J.B. et al., Long-lasting effects of undernutrition, Int. J. Environ. Res. Public Health, 8 (2011) 1817-1846.
Iran
Research Report
2011
HOSSEINI-ESFAHANI, F., et al., Trends in risk factors for cardiovascular disease among Iranian adolescents: the Tehran Lipid and Glucose Study, 1999-2008. J. Epidemiol. 21 (2011) 319-328.
Mexico
Research Report
2012
RAMIREZ, E., et al., Body composition prediction equations based on deuterium oxide dilution method in Mexican children: a national study, Eur. J. Clin. Nutr. 66 (2012) 1099-1103.
Malaysia
Research Report
2011
WEE, B.S. et al., Risk of metabolic syndrome among children living in metropolitan Kuala Lumpur: a case control study, BMC Public Health 11 (2011) 333-339
Morocco
Research Report
2012
HAMRANI, A., et al., Fat-free mass prediction model for Moroccan adolescents by bioelectrical impedance analysis using deuterium oxide dilution as a reference, Int. J. Body. Comp. Res. 10 (2012) 107-114.
China
Research Report
2010
LIU, A., et al., Waist circumference cut-off values for the prediction of cardiovascular risk factors clustering in Chinese school-aged children: a cross-sectional study. BMC Public Health 10 (2010) 82-90.
Malaysia
Research Report
2010
QUAH, Y.V., POH, B.K., ISMAIL, M.N., Metabolic syndrome based on IDF criteria in a sample of normal weight and obese school children, Malays. J. Nutr. 16 (2010) 207-217.
Lebanon
Research Report
2010
NASREDDINE, L., et al., 2010, Metabolic Syndrome and Insulin Resistance in Obese Pre-Pubertal Children in Lebanon: A Primary Health Concern. Ann. Nutr. Metabol. 57 (2010) 135-142.
China
Research Report
2011
LIU, A., et al., Ethnic differences in the relationship between body mass index and percentage body fat among Asian children from different backgrounds, Bri. J. Nutr. 106 (2011) 1390-1397.
Morocco
Research Report
2012
MEHDAD, S., et al., Body mass index, waist circumference, body fat, fasting blood glucose in a sample of Moroccan adolescents aged 11-17 years, J. Nutr. Metabol. (2012) Article ID 510458, 7 pages.
Bangladesh
Research Report
2012
KHAN, A.I., et al., Body composition of Bangladeshi children: comparison and development of leg-to-leg bioelectrical impedance equations, J. Health Popul. Nutr. 30 (2012) 281-290.
Brazil
Research Report
2009
SANTOS, C.D.L. et al., Influencia do deficit de estatura nos desvios nutricionais em adolescentes e pré-adolescentes. Revista de Nutri??o 22 (2009) 187-194.
Brazil
Research Report
2011
CLEMENTE, A.P. et al., Mild stunting is associated with higher body fat: study of a low-income population, J. Paediatr. (Rio J.) 87 (2011) 138-144.
India
Research Report
2012
JOSE, B. et al., Serum magnesium in overweight children, Indian Pediatr. 49 (2012) 109-112.
China
Research Report
2011
WANG, X. et al., A bioelectrical impedance prediction equation for the assessment of total body water and fat-free mass among Chinese children aged 7-10 year. Chinese Journal of Prevention and Control of Chronic Disease 19 (2011) 441-444.
Jamaica
Research Report
2010
CAMPBELL, C.P., et al., Predictors of physical activity energy expenditure in Afro-Caribbean children, Eur. J. Clin. Nutr. 64 (2010) 1093-1100.
China
Research Report
2011
LIU, A., et al., Validation of bioelectrical impedance analysis for total body water assessment against the deuterium dilution technique in Asian children, Eur. J. Clin. Nutr. 65 (2011) 1321-1327.
Iran
Research Report
2010
MIRMIRAN, P., et al., Performance of different definitions of metabolic syndrome for children and adolescents in a 6-year follow-up: Tehran Lipid and Glucose Study (TLGS). Diabetes Res. Clin. Pract. 89 (2010) 327-333.
Brazil
Research Report
2012
CLEMENTE, A.P. et al., Mild stunting is associated with higher blood pressure on overweight adolescents, Arq. Bras. Cardiol. 98 (2012) 6-12.
Lebanon
Research Report
2012
NASREDDINE, L., et al., Obesity is associated with insulin resistance and components of the metabolic syndrome in Lebanese adolescents, Ann. Hum. Biol. 39 (2012) 122-128.
Brazil
Research Report
2010
SANTOS, C.D.L. et al., Adolescents with mild stunting show alterations in glucose and insulin metabolism. J. Nutr. Metabol. (2010), Article ID 943070, 6 pages.
Iran
Research Report
2012
BARZIN, M., et al., The association of anthropometric indices in adolescence with the occurrence of the metabolic syndrome in early adulthood: Tehran Lipid and Glucose Study (TLGS).
China
Research Report
2011
LIU, A., et al., Ethnic differences in body fat distribution among Asian pre-pubertal children: a cross-sectional multicenter study, BMC Public Health 11 (2011) 500-506.
China
Research Report
2009
LIU, A., et al., Relationship between anthropometric parameters and lipids profiles (2009) (published in Chinese)
Malaysia
Research Report
2011
POH, B.K., et al., Waist circumference percentile curves for Malaysian children and adolescents aged 6.0-16.9 years, Int. J. Pediatr. Obes. 6 (2011) 229-235.