Total Cholesterol = 190; HDL = 40; LDL = 88 (on statins).
Glucose: 0.93, HbA1C = 6.7 % (on insulin + metformin).
Teaching points:
MPS investigates the pathophysiological consequences of luminal obstructive CAD, while CTA indicates the presence, extent and location of coronary atherosclerosis.
For pratical purposes, CTA excludes CAD (high NPV).
A negative CTA implies no need of MPS on follow-up.
A positive CTA (if performed initially) implies the need for a MPS for short-term prognosis and eventual revascularization, because of low PPV.
Combined anatomical and functional assessment may allow improved risk stratification.
