This special issue of the Food and Nutrition Bulletin considers the application the retinol isotope dilution method in evaluating the safety of vitamin A supplementation under large scale intervention programs. It also delves into strengths and limitation of mathematical modelling approaches for assessment of whole-body vitamin A status.
If you would like to learn more about the IAEA’s work, sign up for our weekly updates containing our most important news, multimedia and more.
Guidance Material
Vitamin A Body Stores
Here you will find the most up to date field and laboratory procedures related to vitamin A status assessment and evaluation of intervention programs using the retinol dilution method.
Assessing Vitamin A Safety in Large-Scale Nutrition Intervention Programmes: Setting the Research Agenda
Proceedings from an IAEA technical meeting held at the St. John’s Research Institute in Bangalore, India from 7-9 October 2013
This a collection of paper focusing on the application of retinol isotope dilution approach in assessment of vitamin A status and value from food.
Handbook on Vitamin A Tracer Dilution Methods to Assess Status and Evaluate Intervention Programs
This Handbook describes the application the retinol isotope dilution method in measuring vitamin A supplementation status and evaluating intervention programs. It covers:
- a description of the stable isotope dilution technique;
- study protocols for using paired stable isotope dilution technique;
- paired stable isotope dilution technique for estimating relative vitamin A equivalency factors for β-carotene;
- monitoring the effectiveness of vitamin A intervention programs and;
- studies on vitamin A requirements.